CIAPM Request for Proposals 2019 - FAQs

Can the proposal have multi-PIs, with the primary institution identified, or is it PI, Co-PI, and then key faculty personnel as Co-Is?

Only one "Lead PI" should be designated as the primary project contact, with partner "PIs" from the same or different organizations. Teams are welcome to call other investigators by any preferred term. We suggest other individuals are grouped as "Key Team Members, Collaborators, and/or Contractors/Consultants.

Which start date should be listed for the Milestones section?

The project start date is flexible, according to the team's preference, any date from May 1 to May 31, 2021.

Is any formal subaward/contract paperwork required for the Full Proposal?

No formal subaward paperwork is required for the Full Proposal. Confirmation of partners' involvement should merely be included in the form of their (wet or electronic) signatures on the Cover Page. Once the awardees are named in March, we will dive head-first into the contracting process.

On the cover page, do all signatures need to be wet or will electronic signatures suffice?

Wet or Electronic signatures are equally acceptable.

Are references to be included in the Concept Proposal and do they count towards the three-page limit?

Yes, any references should be included in the three-page proposal. Typically, concept proposals include only a few key citations.

Should letters of support be included with the Concept Proposal?

No, please include letters of support only with the Final Proposal, due October 28.

Would it be possible to use grant funds to pay an out-of-state trainer to provide a workshop and provide ongoing supervision throughout the study?

All project PIs and key personnel must reside in California. A consultant or contractor who resides outside of California may receive funds from a CIAPM grant. For amounts over $50,000 total per individual, written justification must be included in the final application.

What is the definition of an Adverse Childhood Experience, for purposes of this RFP?

CIAPM follows the guidance of the landmark study by the U.S. Centers for Disease Control and Kaiser Permanente, which describes ten categories of adversities experienced before age 18, organized across three domains: abuse, neglect, and/or household dysfunction.

How does CIAPM define Indirect Costs?

Indirect Costs are what NIH defines as "Facilities and Administrative Costs" and include accounting and legal expenses, administrative salaries, office expenses, rent, utilities, and similar expenses that are incurred for common or joint objectives and cannot be identified readily and specifically with a particular project. Salaries for Study Coordinators, Patient Navigators, Counselors, and Research Assistants, who are all considered members of the project team, would be fully supported as Direct Costs.

I represent a research team that has not previously received funds from CIAPM, but we are housed within a university/institution that is currently funded (from the 2018 RFP). Is my team eligible to apply for this funding opportunity?

Yes, any new team would be eligible and highly encouraged to submit a proposal. CIAPM will not accept proposals from previously or currently funded teams, but other research teams from previously funded institutions are very welcome.

Does a teaching hospital that conducts medical research meet the definition of an "academic research institution"?

Yes, accredited teaching hospitals that conduct medical research are eligible to serve as the "Primary Institution."

Must a project community partner be non-profit?

At least one PI on the proposal must represent a non-profit community/patient organization or county health institution that provides support to people with ACEs.

What are the instructions for the format and contents of the Full Proposal (Stage 3)?

Instructions for composing and submitting full proposals will be provided to finalists by August 31, 2020. Institutional cover letters will be required for full proposal submission. The submission deadline for Full Proposals is October 28, 2020.

What are the selection criteria for the full proposals?

The selection criteria are posted on the website and will not differ throughout the selection process, from concept proposal review and full proposal review.

How can I access the RFP Informational Webinar?

If you were unable to join live, you may still view a recording of the webinar.

Can project teams include multiple community organizations as partners?

Absolutely! ACEs compose a complex field that requires many partners with different perspectives and areas of expertise.

What is the source of funding for this Request for Proposals (RFP)?

Funding for this RFP is provided by the State of California and administered by the Governor’s Office of Planning and Research (OPR).

How should proposal materials be submitted?

All proposal materials must be submitted electronically in PDF format by the Lead Principle Investigator (Lead PI) via the CIAPM Submission Portal. Applications may be re-opened (even after clicking the “Submit” button) any time prior to the submission deadline.

Will the Letter of Intent be scored by the Selection Committee?

No. The Letters of Intent will be used exclusively to inform CIAPM staff of the optimal composition of the Selection Committee, in order to cover as many areas of expertise as are presented among the complete portfolio of proposals.

May I change some project details between the submission of the Letter of Intent and the submission of the Concept Proposal?

Yes, however, the Lead PI must not change and the general theme of the project must remain intact.

Does the RFP limit the number of proposals each institution may submit?

This RFP does not limit the number of proposals each institution may submit or otherwise be included in as a partner. However, not more than one project will be awarded per Primary Institution (primary affiliation of the Lead Principle Investigator).

What institutions are eligible to participate?

The RFP requires that application teams include, at a minimum, Principle Investigators (PIs) from two types of institutions: 1) public or private academic research institutions and 2) nonprofit community/patient organizations or county institutions that provide services to people with ACEs. The institution of the Lead PI is considered the Primary Institution and must be a public or private academic research institution. Other PIs, project team members, and key collaborators may be affiliated with any type of public or private entity within California, such as tribal organizations, health care providers, private industry, education systems, and venture capital.

What counts as a nonprofit patient/community organization or county institution that provides care to people with ACEs?

Examples of eligible nonprofit institutions include patient advocacy organizations, community organizations that coordinate services for adults and/or children with ACEs, community clinics and hospitals, county health and behavioral health agencies, and Federally Qualified Health Centers that provide services to people with ACEs. CIAPM does not intend to be overly proscriptive of qualifying institutions.

What is the Precision Medicine Asset Inventory?

The CIAPM website includes a new, interactive mapping tool, called the “California Precision Medicine Asset Inventory” for members of any organization relevant to health, healthcare, and health equity to better understand the landscape of California-based researchers, community organizations, clinicians, industry, datasets, and other resources relevant to Precision Medicine. Many applicants may find the platform helpful for searching for potential research partners. If you are interested in having your information as an individual and/or organization posted to this platform, please submit the CIAPM Asset Inventory Survey.

Can CIAPM assist me in finding collaborators for my proposal?

Teams seeking project collaborators should directly contact potential partners to gauge their interest. The CIAPM team is also available to facilitate connections, whether for the development of proposals, the strengthening of proposals after the concept proposal submission deadline, or otherwise. Any other inquiries about how the CIAPM team can help facilitate collaborations can also be sent to CIAPM staff.

What are the restrictions on proposal budgets?

Proposals should not include any indirect costs. CIAPM has not identified any additional budget item restrictions but reserves the right to make determinations on a case-by-case basis. If a concept proposal includes a budget item that CIAPM deems to be ineligible for use of CIAPM funds, the CIAPM team will contact the project team and ask for the item to be excluded if the team is invited to submit a full proposal. The inclusion of a budget item deemed to be ineligible will not adversely impact the proposal in the concept proposal selection process. Please direct any questions about specific budget items to CIAPM staff.

Should I include in my proposal the development of a data sharing platform?

The RFP describes that funds may become available for awarded project teams to examine and potentially select and use a common data-sharing platform. This step will occur following the selection of demonstration projects; selected project teams will work together to explore what is possible to share across projects and potentially scale beyond them. This step will occur regardless of how many awarded projects include their own data sharing platform components, so proposals may include the development and use of common data sharing platforms across project partners. If so, please describe why this is beneficial to the project, how it is distinctive, and whether it might be scalable, and include funding for the data sharing component in the budget. However, since there is limited space to explain your project in the concept proposal, it is advisable to not devote too much of it to the data sharing component.

What factors will the Selection Committee consider during the final decision process?

The authorizing statute identifies a breadth of possible focus areas for proposals to improve health outcomes for patient populations with ACEs backgrounds, as listed in the RFP. These focus areas and selection criteria are reflective of the diverse fields and goals that comprise precision medicine. In order to maximize the overall impact of the funded portfolio of projects, the Selection Committee will select a balanced portfolio that represents diversity in several areas, including but not limited to, approaches, research focus areas, patient populations, host institutions, and partners during its deliberations. Thus, while selecting highly meritorious proposals based on final overall impact scores of the individual proposals, the Selection Committee will take into consideration these factors when making funding recommendations to OPR. Finally, as required by statute, the Selection Committee will ensure the inclusion of host institutions in both northern and southern California.

Will project teams that include individuals/institutions that have already been granted CIAPM funds be viewed less favorably than others?

No. Prior receipt of CIAPM funds will not be a consideration in the demonstration project selection process.