News and Events
The CIAPM network of grantees, advisors, patient communities, collaborators, partners, and supporters push the boundaries of precision medicine every day in California and beyond, upholding principles of health equity, scientific rigor, and impact-driven cooperation.
February 19, 2021
February marked the kickoff for both of the Council's working groups. Each is focused on addressing specific health disparities: integrating social determinants of health data into electronic health records, and creating a framework for an equitable consent process that brings more undderrpresented minority groups into medical research.
The first meeting of the Data Integration working group took place on February 8. The group discussed several existing efforts to standardize social determinants of health for electronic health records, and possible partnerships and synergies between public, private, and nonprofit organizations. The Data Integration group is chaired by Hakan Sakul, PhD, who is a Vice President and Head of Diagnostics at Pfizer.
Hakan Sakul, PhD
Chair, Data Integration Working Group
The first meeting of the Equitable Consent working group took place on February 19. The members contributed ideas on the development of an equitable framework for the informed consent process that takes place in the course of research on human subjects, and strategized how to maximize the impact of the project. The group is chaired by Kenneth Kim, MD, a physician who is the founder and Chief Medical Officer for Ark Clinical Research.
Kenneth Kim, MD
Chair, Equitable Consent Working Group
Each working group will meet every other month, and meetings will be open to the public. Check the Meetings page for agendas and registration details.
February 18, 2021
The California Council on Science & Technology (CCST) engaged CIAPM in an agenda-setting workshop on February 18 as part of their new Disaster Resilience Initiative, an effort to bridge science and technology experts with state policymakers. Sharing the virtual panel with California Health and Human Services Assistant Secretary Marko Mijic and Assemblymember Dr. Bill Quirk, CIAPM Co-Director Dr. Julianne McCall presented to deans, chief science officers, chief innovation officers, professors, and other experts representing California's world-class research institutions, including CIAPM Advisor Dr. Bonnie Maldonado. Discussion about the most pressing policy and research challenges in our state touched on the digital divide, an impending mental health crisis, rampant public health misinformation, economic strains, workforce development, and data infrastructure. Policy Fellows Aiyana Emigh Cortez and Hyunsoo Gloria Kim contributed to post-panel discussions and exercises.
First-ever California Surgeon General's Report Released
December 9, 2020
The first-ever California Surgeon General’s Report was released, titled Roadmap for Resilience: The California Surgeon General’s Report on Adverse Childhood Experiences, Toxic Stress, and Health. This report was co-authored by CIAPM Co-Director Dr. Julianne McCall, with contributions from Co-Director Dr. Shannon Muir, former Science Fellow Dr. Ken McCullough, and Policy Fellow Gloria Kim, design by Science Communications Specialist and Administrator Megan Varvais, and reference management by Policy Fellows April Booth and Aiyana Emigh Cortez.
The 438-page report is a product of experts across specialties and geographic areas. Organized around primary, secondary, and tertiary prevention strategies, the report includes stand-alone summaries for various sectors, including health care, education, early childhood, justice, and social services.
California Surgeon General Dr. Nadine Burke Harris presented key findings from the report in a public webinar, recorded and accessible here.
We at CIAPM were honored to partner with the Office of the California Surgeon General to develop this important resource and look forward to continuing to advance the science of ACEs with the announcement of awardees of our ongoing Request for Proposals for ACEs research in March.
Key Steps to Reduce Racial Cancer Disparities Include Supporting Minority Scientists, Diversifying Medical Schools and Clinical Trials
September 25, 2020
Former CIAPM Advisor John Carpten, PhD, addressed Congress this month as the Chair of the inaugural AACR Cancer Disparities Progress Report 2020, published September 16 by the American Association of Cancer Research. In his presentation to Congress and a recent interview for the American Journal of Managed Care (AJMC), he discussed the root causes of racial inequality in cancer care, how inequality in research leads to disparities in outcomes and mortality, and how cancer researchers can change these circumstances.
John Carpten, PhD
Dr. Carpten is the Chair of the Department of Translational Genomics at the University of Southern California (USC) and co-leads the Translational and Clinical Sciences Program at the USC Norris Comprehensive Cancer Center. Dr. Carpten was a member of the Precision Medicine Advisory Committee, which produced the 2018 report Precision Medicine: An Action Plan for California.
Dr. David Haussler Accelerates COVID-19 Research and Celebrates 20 Years Since the First Draft Sequence of the Human Genome
August 20, 2020
This summer, the National Human Genome Research Institute celebrated 20 years since Dr. David Haussler and his team at UC Santa Cruz uploaded the first working draft sequence of the human genome. Not long after, the UCSC Genome Browser was released, enabling graphical visualization of the data. The framework continues to provide researchers the opportunity to contribute their findings for others to use. Since its release, the UCSC Genome Browser has been used extensively, nearing 40,000 citations in the literature.
In the early days of the pandemic, Dr. Haussler's team worked to adapt the UCSC Genome Browser to provide researchers around the world with a common platform to access the latest molecular data characterizing the SARS-CoV-2 genome and proteins. Scientists can use the community resource to analyze how the virus has mutated, compare the genome with other coronaviruses, and upload their own findings to further shared understanding. A manuscript was recently posted with full details.
Dr. Haussler is the Scientific Director of the UC Santa Cruz Genomics Institute and was one of CIAPM's first grantees in 2015.
California Precision Medicine Advisory Council holds its first meeting, selects leadership
May 15, 2020
The California Precision Medicine Advisory Council (CPMAC) held its first meeting on May 12 and 15, 2020. Both sessions were through videoconference. The Council selected Clara Lajonchere, PhD to be Chair and Keith Yamamoto, PhD for Vice Chair. Dr. Lajonchere is the Deputy Director of the Institute for Precision Health at UCLA's David Geffen School of Medicine. Dr. Yamamoto is Vice Chancellor for Science Policy and Strategy at UCSF.
Information about the CPMAC’s meetings, including minutes, can be found on the Meetings page.
CIAPM-Supported Research Advances Pandemic Response
April 3, 2020
A CIAPM grant recipient is using the techniques he refined and expanded as a Principle Investigator to sequence viral genomes from hundreds of COVID-19 patients, informing health officials of how the virus is mutating and spreading around the world. Charles Chiu, MD, PhD, an infectious disease physician and professor of laboratory medicine at University of California San Francisco, received the grant in 2015 for his project “Precision Diagnosis of Infectious Diseases.” Dr. Chiu conducted the research in collaboration with four other Universities of California, the Department of Public Health, a number of California-based companies, and other partners.
Read more in the press:
CIAPM Grantee Helps Characterize COVID-19
April 2, 2020
New research from Dr. Brennan Spiegel, MD and a Wuhan-based medical team sheds light on a lesser-known form of COVID-19. While the coronavirus pandemic continues to unfold, doctors and scientists around the world are rapidly developing diagnostic tests, searching for possible treatments, testing vaccine candidates, and caring for patients using every medical tool and technique available. Those critical efforts depend on a comprehensive understanding of how COVID-19 impacts all patients, not just the majority. Dr. Spiegel serves as Director of Health Services Research at the Cedars-Sinai Health System in Los Angeles and is a 2017 CIAPM grant recipient for research in cardiology and remote biosensors.
While the most prevalent and threatening symptoms of COVID-19 are respiratory, the research team found that some patients with a more mild form of the disease experience gastrointestinal problems before or entirely without any of the commonly associated symptoms, like fever, cough, and shortness of breath. Such patients tend to be diagnosed later than others, and are at-risk of spreading the virus for days without suspecting they would test positive for the disease.
Read the pre-published study made available by the American Journal of Gastroenterology and national press coverage:
Announcing the New California Precision Medicine Advisory Council
February 26, 2020
The Newsom Administration has created a new California Precision Medicine Advisory Council (CPMAC) to provide high-level guidance to the Governor’s Office of Planning and Research (OPR) on matters relating to CIAPM. OPR selected the members in close coordination with the Governor’s Office and Legislative leadership. The Advisors represent a broad range of sectors including patient advocacy and community groups, academia, private industry, health policy, clinical providers, venture capital, and philanthropy. They have expertise in a variety of precision-medicine related fields, including data science, bioinformatics, pharmacology, community engagement, medical devices, and public health, among others.